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They can also treat pain from an injury or surgery.Hydrocodone is intended for severe chronic pain when nonopioid pain relievers, such as ibuprofen and acetaminophen, haven’t helped. They’re both highly effective, but they work in different ways. Here’s what to know about how tramadol and hydrocodone are similar and different.

If you feel yourself becoming dependent, contact your doctor right away.

Certain people may be more at risk of side effects.

Side effects of both drugs are more likely or can be more intense if you are a senior.

It is believed that this helps block pain signals in your spinal cord.

Generic available—Yes Brand name—Con Zip, Ultram Forms—Immediate-release tablets and extended-release tablets Strengths—Immediate release: 50 mg; extended release: 100 mg, 150 mg, 200 mg, 300 mg Unique side effects: Generic available—No Brand name— Zohydro ER, Hysingla ER Forms—Extended-release tablets (Immediate-release hydrocodone is only available in combination products in which it’s combined with other drugs.) Strengths—Extended release: 20–120 mg Unique side effects: Get immediate medical attention or call 911 if you have any serious side effects from either drug.

Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency.

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